14 January 2025

Polo-like kinase inhibitors increase AAV production by halting cell cycle progression

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17 November 2024

Transcriptomics-informed pharmacology identifies epigenetic and cell cycle regulators that enhance AAV production

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15 October 2024

From chemical to mechanical: A comparative analysis of cell lysis strategies for mammalian cells

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15 October 2024

Considerations for AAV analytical comparability studies for products with low batch numbers

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15 October 2024

Two for one: A single QC assay to quantify two plasmid impurities (cap/kanR) across a number of serotypes reduces time & costs for rAAV batch release

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15 October 2024

Streamlined pre-formulation screening with minimal sample requirements & ​2-day turnaround to enable high efficiency ​AAV formulation development

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15 October 2024

Advancements in nanopore sequencing allow ​in-depth characterization of rAAV vector batches comparable to SMRT™ sequencing

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15 October 2024

Qualification of an mRNA expression assay for GOI, stability insights, and process evolution detection

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15 October 2024

Successful capture DoE studies for a range of AAV serotypes to reduce manufacturing costs & accelerate development

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15 October 2024

Development & qualification of potency assay : guidelines and strategy​

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15 October 2024

Assessing device compatibility through assay matrix approach ensures therapeutic consistency & patient welfare

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15 October 2024

Nanopore sequencing grants detailed insights into a ​small molecule’s impact on encapsidated DNA​ composition during manufacturing platform development

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