Unveiling the AAV8 Full Empty Separation Potential of Three Resins for Platform Innovation

19 June 2026

by Ascend Advanced Therapies

In this walkthrough of our 2026 ASGCT poster, we share an evaluation of the ability of three chromatographic resins to separate full from empty AAV8 capsids—a critical step in gene therapy vector production.

The study systematically compares the resins under scalable anion exchange chromatography (AEX) conditions, focusing on vector genome recovery, impurity clearance, separation efficiency, and product quality.

Learn more about Ascend’s process development capabilities for AAV and other advanced therapy products.

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